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CYCLIC GMP-DEPENDENT PROTEIN KINASE TYPE I
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DeCS
Descriptor
English
:
Cyclic GMP-Dependent Protein Kinase Type I
Descriptor
Spanish
:
Proteína Quinasa Dependiente de GMP Cíclico Tipo I
Descriptor
Portuguese
:
Proteína Quinase Dependente de GMP Cíclico Tipo I
Tree Number:
D08.811.913.696.620.682.700.150.150.500
D12.644.360.200.150.500
D12.776.476.200.150.500
Definition
English
:
A cyclic GMP-dependent protein kinase subtype that is expressed in SMOOTH MUSCLE
tissues
and plays a role in regulation of smooth
muscle contraction
. Two isoforms, PKGIalpha and PKGIbeta, of the type I protein kinase exist due to
alternative splicing
of its mRNA.
History Note
English
:
2013
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
54933
Unique Identifier:
D062965
Occurrence in VHL
:
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CID-10
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